Over the years, medical science has been continuously evolving to accommodate any changes in the medical landscape. It does not cease from looking for solutions and treatments of various diseases. The discovery of liposome is among the most remarkable breakthroughs in the industry. This is used to aid drug intake to enhance its efficiency, increase success rate in organ transplant surgery and treat several medical malfunctions.
Liposomes are microscopic vesicles that are developed in a laboratory. These are made from phospholipids that may be produced naturally or extracted from other sources. The outer wall of the liposome is composed of lipids that are similar to the composition of cell walls. Hence, the liposomes can directly interact with the cells. These tiny, spheroid bubbles typically have a watery core.
This structure is most commonly used in introducing medicines to the patient's body. Using this as a drug vessel has proven to be more effective than any other methods of administering the medications. The vesicles are uniquely designed to deliver the drugs to a particular part of the human body through the diffusion process. This makes it a perfect choice for administering antibodies to directed parts of the body. This can also carry hydrophobic drugs because of its double-layered membrane.
Moreover, this can extend the delivery time of the administered drugs. The bi-layered sphere slowly releases the drugs in interval over a period of time. This is hypothetically believed to help reduce side-effects since the direct impact of the applied medications are limited only to the affected tissues. This also means that the efficiency of the drugs is maximized.
This is also believed to be a natural cancer fighting agent. The spheroid-shaped vesicle can be used in targeting the cancer cells by slipping right through the tumor through blood flow. Cancer cells are noted to be leaky in nature, allowing even small particles to escape. Yet, since human blood vessels cannot get pass the endothelial wall and the liposomes have similar structure, it can stay in the bloodstreams.
This can also help fight autoimmune diseases. In most transplant surgeries, the body initially identifies the newly transplanted organ as a foreign object. As a result, the immune system will try to attack it as the body's natural reaction to protect itself from infestation. This can lead to the body's rejection of the harvested organ. The artificial lipid can help suppress the immune system to slow down its progression.
The vesicles are not spontaneously produced, though. There are various methods used to create these drug vessels according to its function and purpose. Its method of dissemination must be considered as well as the type of materials that will be transported.
The vesicles can be produced in varying sizes. Typically, these are developed small enough so the white blood cells can easily engulf it before releasing the drug it carries. Decision has to be made before production to know the size and number of vesicles to be produced. If there is a need, reproduction must also be considered.
One reservation for medical practitioners regarding this extremely useful breakthrough is its production costs. Mass production is currently unavailable since the vessels cannot last long after its creation. There has been cases of instability and unintentional mixture of drugs as well. Other than that, liposome is definitely a promising discovery.
Liposomes are microscopic vesicles that are developed in a laboratory. These are made from phospholipids that may be produced naturally or extracted from other sources. The outer wall of the liposome is composed of lipids that are similar to the composition of cell walls. Hence, the liposomes can directly interact with the cells. These tiny, spheroid bubbles typically have a watery core.
This structure is most commonly used in introducing medicines to the patient's body. Using this as a drug vessel has proven to be more effective than any other methods of administering the medications. The vesicles are uniquely designed to deliver the drugs to a particular part of the human body through the diffusion process. This makes it a perfect choice for administering antibodies to directed parts of the body. This can also carry hydrophobic drugs because of its double-layered membrane.
Moreover, this can extend the delivery time of the administered drugs. The bi-layered sphere slowly releases the drugs in interval over a period of time. This is hypothetically believed to help reduce side-effects since the direct impact of the applied medications are limited only to the affected tissues. This also means that the efficiency of the drugs is maximized.
This is also believed to be a natural cancer fighting agent. The spheroid-shaped vesicle can be used in targeting the cancer cells by slipping right through the tumor through blood flow. Cancer cells are noted to be leaky in nature, allowing even small particles to escape. Yet, since human blood vessels cannot get pass the endothelial wall and the liposomes have similar structure, it can stay in the bloodstreams.
This can also help fight autoimmune diseases. In most transplant surgeries, the body initially identifies the newly transplanted organ as a foreign object. As a result, the immune system will try to attack it as the body's natural reaction to protect itself from infestation. This can lead to the body's rejection of the harvested organ. The artificial lipid can help suppress the immune system to slow down its progression.
The vesicles are not spontaneously produced, though. There are various methods used to create these drug vessels according to its function and purpose. Its method of dissemination must be considered as well as the type of materials that will be transported.
The vesicles can be produced in varying sizes. Typically, these are developed small enough so the white blood cells can easily engulf it before releasing the drug it carries. Decision has to be made before production to know the size and number of vesicles to be produced. If there is a need, reproduction must also be considered.
One reservation for medical practitioners regarding this extremely useful breakthrough is its production costs. Mass production is currently unavailable since the vessels cannot last long after its creation. There has been cases of instability and unintentional mixture of drugs as well. Other than that, liposome is definitely a promising discovery.
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